Healthy Skinfluence

Tetrasodium Edetate

Tetrasodium Edetate

TET
9/10
Concern level
High concern

Tetrasodium Edetate is the fully neutralized sodium salt of EDTA, used in cosmetics primarily as a chelating agent. It binds trace metal ions from water and raw materials to improve formula stability, reduce discoloration, and help protect preservatives and antioxidants from metal-catalyzed degradation. It is not an exfoliant or treatment active; its main role is formulation support. In higher-concentration solutions it is alkaline and can be irritating, but at typical cosmetic use levels it is generally considered low-risk and broadly compatible with rinse-off and leave-on products.

Pore-clogging
Non-comedogenic
Pregnancy
Safe
Regulatory
No data

Chemical Properties

Molecular Weight
380.17 g/mol
pH Range
4.00 - 11.00
Typical Concentration
0.01% - 0.50%
CAS Number: 64-02-8

Skin Type Compatibility

dry skin9/10
oily skin9/10
sensitive skin8/10
acne prone9/10
mature skin9/10
normal skin9/10

Interactions

incompatible with: strongly cationic preservatives or actives may be affected by chelation, formulas relying on metal-ion stability should be re-tested if EDTA level changes, avoid relying on concentrated raw material near eyes due to alkalinity

Risks & Warnings

Main risks are formulation-related rather than skin-directed: concentrated solutions are alkaline and may irritate eyes or skin. It may increase penetration of some ingredients by altering metal-ion interactions, so high-pH or high-load formulations should be tested carefully. Avoid direct use of concentrated raw material on skin or around the eyes. No meaningful comedogenic risk is expected.

Vegan Cruelty-Free

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