Symphytum Officinale Root Extract

SYM

3/10

Concern level

Low concern

Botanical root extract from comfrey (Symphytum officinale), traditionally used in topical products for soothing and skin-comfort benefits. It contains constituents such as allantoin and rosmarinic acid, but also pyrrolizidine alkaloids (PAs), which are the main safety concern. ([ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/books/NBK548370/?utm_source=openai))

Pore-clogging

Non-comedogenic

Pregnancy

Caution

Regulatory

No data

Benefits

HealingSoothing

Chemical Properties

Typical Concentration

5.00% - 30.00%

Skin Type Compatibility

dry skin5/10

oily skin3/10

sensitive skin2/10

acne prone3/10

mature skin4/10

normal skin5/10

Interactions

incompatible with: Avoid use on broken, abraded, or inflamed skin due to increased absorption risk. ([sciencedirect.com](https://www.sciencedirect.com/science/article/pii/S0273230020302105?utm_source=openai)), Use caution when layering with other potentially irritating actives if the barrier is compromised. ([ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/books/NBK548370/?utm_source=openai))

Risks & Warnings

Main concern is pyrrolizidine alkaloid exposure, which is associated with hepatotoxicity and has been linked to severe liver injury; risk increases with prolonged use, use on broken skin, or systemic exposure. Not recommended in pregnancy or breastfeeding due to toxicity concerns and limited safety data. ([ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/books/NBK548370/?utm_source=openai))

Vegan Cruelty-Free

Found In Products

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