Symphytum Officinale Leaf Extract**

SYM

3/10

Concern level

Low concern

Comfrey leaf extract is a botanical skin-conditioning ingredient associated with allantoin- and phenolic-rich fractions, but it can also contain pyrrolizidine alkaloids (PAs). Those PAs are the main reason comfrey is treated as a higher-caution ingredient, especially for prolonged use or broken skin. ([ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/books/NBK548370/?utm_source=openai))

Pore-clogging

Non-comedogenic

Pregnancy

Caution

Regulatory

No data

Benefits

HealingSoothing

Chemical Properties

Typical Concentration

0.10% - 1.00%

CAS Number: 84696-05-9

Skin Type Compatibility

dry skin5/10

oily skin4/10

sensitive skin2/10

acne prone4/10

mature skin5/10

normal skin4/10

Interactions

incompatible with: avoid on broken or compromised skin, avoid during pregnancy and breastfeeding, avoid prolonged or large-area use

Risks & Warnings

Primary concern is pyrrolizidine alkaloid exposure, which is linked to hepatotoxicity and potential carcinogenicity; avoid oral exposure and avoid topical use on broken skin or for long-duration/large-area application. This ingredient is not a good choice for pregnancy or breastfeeding use. ([ncbi.nlm.nih.gov](https://www.ncbi.nlm.nih.gov/books/NBK548370/?utm_source=openai))

Vegan Cruelty-Free

Found In Products

JOSIE MARAN