Healthy Skinfluence

Symphytum Officinale Leaf Extract

Symphytum Officinale Leaf Extract

SYM
2/10
Concern level
Low concern

Botanical extract from comfrey leaves (Symphytum officinale) used in skincare for soothing, conditioning, and traditional wound-care style claims. Leaf and root extracts contain allantoin, rosmarinic acid, tannins, and other plant constituents; however, comfrey is also associated with pyrrolizidine alkaloids (PAs), which are the main toxicological concern.

Pore-clogging
Non-comedogenic
Pregnancy
Caution
Regulatory
No data

Benefits

HealingSoothing

Chemical Properties

pH Range
4.00 - 7.50
Typical Concentration
0.10% - 1.00%
CAS Number: 84696-05-9

Skin Type Compatibility

dry skin4/10
oily skin2/10
sensitive skin2/10
acne prone1/10
mature skin3/10
normal skin3/10

Interactions

incompatible with: avoid with broken or compromised skin barrier, avoid combining with other potentially hepatotoxic botanical actives in leave-on high-exposure products

Risks & Warnings

Primary concern is contamination or intrinsic presence of pyrrolizidine alkaloids, which have been associated with hepatotoxicity and other toxicity concerns. Avoid use on broken, irritated, or damaged skin and avoid prolonged or high-level exposure. Not appropriate for pregnancy/breastfeeding cautionary formulations due to limited safety certainty and toxicology concerns.

Vegan Cruelty-Free

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