Healthy Skinfluence

Symphytum Officinale Callus Culture Extract

Symphytum Officinale Callus Culture Extract

SYM
6/10
Concern level
Moderate concern

A plant cell-culture extract derived from callus tissue of comfrey (Symphytum officinale). In cosmetics it is used as a skin-conditioning and soothing ingredient, and is generally positioned as a safer alternative to whole comfrey extracts because callus cultures are intended to reduce unwanted plant constituents such as pyrrolizidine alkaloids. Available data are limited compared with mainstream cosmetic botanicals.

Pore-clogging
Non-comedogenic
Regulatory
No data

Benefits

HealingSoothing

Chemical Properties

Typical Concentration
0.40% - 1.00%

Skin Type Compatibility

dry skin7/10
oily skin6/10
sensitive skin6/10
acne prone7/10
mature skin7/10
normal skin7/10

Interactions

incompatible with: No specific direct interactions are well established. Exercise caution in formulas that already contain multiple botanicals or known sensitizers, and verify the raw material is free of pyrrolizidine alkaloids if possible.

Risks & Warnings

Evidence is limited, so overall safety confidence is lower than for more widely studied botanicals. Although callus-culture ingredients are generally processed to avoid the pyrrolizidine alkaloids associated with comfrey, trace contamination or supplier variability cannot be ruled out. Because pregnancy-specific data are insufficient, caution is prudent. Botanical allergy or mild irritation remains possible.

Vegan Cruelty-Free

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