sr-Spider Polypeptide-1**
sr-Spider Polypeptide-1**
SR-
8/10
Concern level
High concern
Peptide Compound
A recombinant spider-derived polypeptide used primarily as a film-forming skin- and hair-conditioning ingredient. It is described as a single-chain protein produced by fermentation, with cosmetic use focused on skin protection, hair conditioning, and nail conditioning. Like many peptide materials, it is generally used at low levels in finished products.
Pore-clogging
Non-comedogenic
Pregnancy
Safe
Regulatory
No data
Benefits
MoisturizingSupports Barrier Function
Chemical Properties
pH Range
4.00 - 7.00Typical Concentration
0.01% - 0.10%Skin Type Compatibility
dry skin7/10
oily skin6/10
sensitive skin7/10
acne prone6/10
mature skin8/10
normal skin8/10
Interactions
incompatible with: No known major incompatibilities with common skincare actives, Use caution in very high-pH formulas that can destabilize protein/peptide materials, As with all peptide materials, validate stability with preservatives, heat, and extreme pH
Risks & Warnings
Overall low-risk ingredient, but as a protein-based material it may rarely contribute to sensitization in highly reactive users. Safety depends on the finished formulation and preservative system. Data on long-term dermal exposure, pregnancy use, and direct comedogenicity are limited.
Vegan Cruelty-Free


