Phosphatidylglycerol

PHO

9/10

Concern level

High concern

Phosphatidylglycerol is a naturally occurring phospholipid found in biological membranes and surfactant systems. In cosmetics, it is mainly used as a skin-conditioning lipid and formulation aid, often in phospholipid/liposomal systems that help support barrier feel, improve spreadability, and enhance delivery of other ingredients. It is generally considered a gentle, biomimetic ingredient rather than an active exfoliant or preservative.

Pore-clogging

Non-comedogenic

Pregnancy

Safe

Regulatory

No data

Benefits

MoisturizingSoothingSupports Barrier Function

Chemical Properties

pH Range

4.50 - 7.50

Typical Concentration

0.10% - 5.00%

CAS Number: 92347-24-5

Skin Type Compatibility

dry skin9/10

oily skin7/10

sensitive skin9/10

acne prone8/10

mature skin8/10

normal skin9/10

Interactions

incompatible with: Can be destabilized by oxidation if paired with poorly protected unsaturated oils, May be less stable in formulas with inadequate antioxidant protection, No well-established direct incompatibilities with common skincare actives were identified

Risks & Warnings

Generally low risk. Potential concerns are limited to individual sensitivity, oxidation/rancidity in lipid-containing systems, or irritation from other ingredients in the finished formula rather than phosphatidylglycerol itself. Avoid use in products with poor preservation or unstable lipid systems.

Vegan Cruelty-Free

Found In Products

rhode