Phloretin

PHL

7/10

Concern level

High concern

Phloretin is a naturally occurring dihydrochalcone flavonoid found in apples and other fruits. In cosmetics, it is used primarily as an antioxidant and brightening active, and it is also described in EU CosIng as an anti-sebum/antioxidant ingredient. It is generally formulated in leave-on antioxidant serums and treatment products, often alongside vitamin C and ferulic acid. PubChem lists its molecular formula as C15H14O5 and molecular weight as 274.27 g/mol. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/Phloretin?utm_source=openai))

Pore-clogging

Non-comedogenic

Regulatory

No data

Benefits

Controls Oil ProductionAnti-agingBrightening

Chemical Properties

Molecular Weight

274.27 g/mol

pH Range

3.00 - 5.50

Typical Concentration

0.10% - 2.00%

CAS Number: 60-82-2

Skin Type Compatibility

dry skin6/10

oily skin8/10

sensitive skin5/10

acne prone7/10

mature skin8/10

normal skin8/10

Interactions

incompatible with: No specific prohibited ingredient interactions are established from the sources reviewed., Commonly paired with vitamin C and ferulic acid in antioxidant serums rather than avoided., Use caution when combining with other potentially irritating strong actives such as retinoids or exfoliating acids if skin is sensitive.

Risks & Warnings

Main concerns are mild irritation or stinging in sensitive skin, especially in low-pH leave-on formulas. Published reviews note limited aqueous solubility and photoinstability, which can complicate formulation. As with most antioxidant actives, it is best paired with daily sunscreen because it does not provide UV protection itself. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/32971088/?utm_source=openai))

Vegan Cruelty-Free

Found In Products

COMPLETE SKIN SOLUTIONS

Phloretin Serum Advanced Formula 1oz

Drunk Elephant

Bouncy Brightfacial Brightening Mask with 10% Azelaic Acid + 1% Salicylic Acid