Palmitoyltripeptide-5

PAL

9/10

Concern level

High concern

Peptide Compound

A synthetic lipopeptide (palmitic acid linked to the tripeptide Lys-Val-Lys) used as an anti-aging cosmetic active. It is designed to support the appearance of firmer, smoother skin and reduce the look of fine lines by helping signal collagen-related pathways. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/Palmitoyl-Tripeptide-5?utm_source=openai))

Pore-clogging

Low

Pregnancy

Safe

Regulatory

No data

Benefits

Boosts Collagen ProductionAnti-agingSupports Barrier Function

Chemical Properties

Molecular Weight

611.9 g/mol

pH Range

4.50 - 7.50

Typical Concentration

0.00% - 3.00%

CAS Number: 623172-56-5

Skin Type Compatibility

dry skin8/10

oily skin6/10

sensitive skin8/10

acne prone7/10

mature skin10/10

normal skin9/10

Interactions

incompatible with: Strongly acidic formulas may reduce peptide stability or performance., High-heat processing can degrade peptide actives., Use caution when combining with very low-pH exfoliating acids in the same leave-on product.

Risks & Warnings

Generally low risk in topical cosmetic use. Main concerns are typical of peptide actives from supplier formulations: potential mild irritation or sensitization in very reactive skin, and formula instability if the finished product is poorly preserved or outside the recommended pH range. Avoid claims of drug-like collagen repair. ([specialchem.com](https://www.specialchem.com/cosmetics/inci-ingredients/palmitoyl-tripeptide-5?utm_source=openai))

Vegan Cruelty-Free

Found In Products

Beauty of Joseon