Palmitoyl Tetrapeptide-10

PAL

8/10

Concern level

High concern

Peptide Compound

Palmitoyl Tetrapeptide-10 is a synthetic lipopeptide made from a tetrapeptide chain linked to palmitic acid. In cosmetics it is used as a skin-conditioning and anti-aging active, typically in very low concentrations. It is generally formulated as part of peptide complexes aimed at supporting a smoother, brighter-looking complexion rather than acting as a strong treatment active.

Pore-clogging

Non-comedogenic

Pregnancy

Safe

Regulatory

No data

Benefits

Anti-agingMoisturizingSoothing

Chemical Properties

Molecular Weight

761 g/mol

pH Range

4.00 - 8.00

Typical Concentration

0.00% - 0.01%

CAS Number: 887140-79-6

Skin Type Compatibility

dry skin7/10

oily skin6/10

sensitive skin8/10

acne prone6/10

mature skin8/10

normal skin8/10

Interactions

incompatible with: strong acids at low pH may reduce peptide stability, high-heat processing can degrade peptides, highly oxidizing systems may reduce activity

Risks & Warnings

Available cosmetic safety reviews suggest low irritation potential when used at customary levels. As with most peptide actives, the main practical risks are formulation instability, reduced efficacy if the product is poorly preserved, and possible mild sensitivity in very reactive skin. No well-established pregnancy-specific concern is known from cosmetic use, but direct pregnancy data are limited.

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