Oligopeptide-177
Oligopeptide-177
OLI
6/10
Concern level
Moderate concern
Peptide Compound
Synthetic cosmetic peptide used as a cell-communicating/skin-conditioning active. It is marketed as part of the TFC8 complex and is described as an erythropoietin-derived peptide intended to support skin renewal, repair signaling, and anti-aging benefits. Publicly available safety and formulation data are limited.
Pore-clogging
Non-comedogenic
Pregnancy
Safe
Regulatory
No data
Benefits
Boosts Collagen ProductionAnti-agingHealing
Chemical Properties
Molecular Weight
3500 g/molTypical Concentration
0.00% - 0.10%Skin Type Compatibility
dry skin7/10
oily skin7/10
sensitive skin6/10
acne prone7/10
mature skin8/10
normal skin7/10
Interactions
incompatible with: No well-established ingredient conflicts in public data, Potential incompatibility is formulation-specific rather than ingredient-specific
Risks & Warnings
Limited publicly available toxicology, irritation, and pregnancy-specific data. As with most peptides, it is generally expected to be low irritation and low comedogenic risk, but evidence is not robust enough for strong safety claims. The main practical risk is formulation-specific sensitivity rather than known inherent hazard.
Vegan Cruelty-Free
