Nicotiana Benthamiana Hexapeptide- 40 sh-Polypeptide-76

NIC

8/10

Concern level

High concern

Peptide Compound

A bioengineered peptide complex produced in Nicotiana benthamiana expression systems, used as a skin-conditioning anti-aging active. It is marketed as a growth-factor-like peptide for supporting the appearance of skin renewal, firmness, and overall barrier-conditioned skin. ([ewg.org](https://www.ewg.org/skindeep/ingredients/862957-NICOTIANA_BENTHAMIANA_HEXAPEPTIDE40_SHPOLYPEPTIDE76/?utm_source=openai))

Pore-clogging

Non-comedogenic

Regulatory

No data

Benefits

Boosts Collagen ProductionAnti-agingSupports Barrier Function

Chemical Properties

Typical Concentration

0.00% - 0.01%

Skin Type Compatibility

dry skin8/10

oily skin6/10

sensitive skin7/10

acne prone6/10

mature skin9/10

normal skin8/10

Interactions

incompatible with: No well-documented incompatibilities; avoid combining with very harsh, low-pH exfoliating systems unless the finished formula has been stability-tested., Use caution when layering with highly irritating actives on highly sensitive skin, since tolerance can be reduced even if the peptide itself is low-irritancy.

Risks & Warnings

Specific human cosmetic safety data are limited. Main concerns are theoretical: low-level irritation or sensitization in very reactive skin, and a precautionary approach in pregnancy because it is a recombinant growth-factor-like peptide with limited pregnancy-specific evidence. ([theskinformulary.com](https://www.theskinformulary.com/ingredients/nicotiana-benthamiana-hexapeptide-40-sh-polypeptide-76?utm_source=openai))

Vegan Cruelty-Free

Found In Products

ALPYN