Healthy Skinfluence

Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76

Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76

NIC
8/10
Concern level
High concern
Peptide Compound

A recombinant, plant-produced peptide ingredient derived using Nicotiana benthamiana expression systems. It functions primarily as a skin-conditioning, anti-aging cosmetic active and is marketed as a retinoid alternative or growth-factor-like peptide for supporting firmness, renewal, and overall skin condition. ([cosmileeurope.eu](https://cosmileeurope.eu/inci/detail/23282/nicotiana-benthamiana-hexapeptide-40-sh-polypeptide-76/?utm_source=openai))

Pore-clogging
Non-comedogenic
Pregnancy
Safe
Regulatory
No data

Benefits

Boosts Collagen ProductionAnti-agingFirming EffectMoisturizingSupports Barrier Function

Chemical Properties

pH Range
4.50 - 7.50
Typical Concentration
1.50% - 2.00%

Skin Type Compatibility

dry skin8/10
oily skin6/10
sensitive skin7/10
acne prone6/10
mature skin9/10
normal skin8/10

Interactions

incompatible with: INSUFFICIENT_DATA: no specific ingredient-level conflicts were identified in authoritative sources; as a formulation-active peptide, compatibility should be validated with strong oxidizers, extreme pH systems, and preservation systems that may degrade proteins. ([cosmileeurope.eu](https://cosmileeurope.eu/inci/detail/23282/nicotiana-benthamiana-hexapeptide-40-sh-polypeptide-76/?utm_source=openai))

Risks & Warnings

Available evidence suggests low irritation and no phototoxicity in cosmetic use, but pregnancy-specific safety data are limited, so caution is prudent. As with other peptide actives, product performance depends on formulation stability and preservation. ([aston-chemicals.com](https://www.aston-chemicals.com/single-product?id=2114&utm_source=openai))

Vegan Cruelty-Free

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