Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76

NIC

7/10

Concern level

High concern

Peptide Compound

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 is a synthetic/biotech-derived fusion peptide used as a skin-conditioning anti-aging active. It combines a hexapeptide component with a recombinant human single-chain polypeptide produced using Nicotiana benthamiana expression systems, and is typically used in small amounts in targeted serums and creams.

Pore-clogging

Non-comedogenic

Pregnancy

Safe

Regulatory

No data

Benefits

Boosts Collagen ProductionAnti-agingSupports Barrier Function

Chemical Properties

Molecular Weight

26000 g/mol

pH Range

4.50 - 7.50

Typical Concentration

0.00% - 0.10%

Skin Type Compatibility

dry skin7/10

oily skin7/10

sensitive skin6/10

acne prone6/10

mature skin9/10

normal skin8/10

Interactions

incompatible with: Strong acids or alkalis that can hydrolyze or denature peptides, High-heat processing, Oxidizing systems that may reduce peptide stability

Risks & Warnings

Safety data in cosmetics is limited compared with established peptides, so conservative use is appropriate. Potential concerns are mainly formulation- or product-specific irritation rather than inherent comedogenicity. Avoid use on broken or highly reactive skin if the finished product contains other sensitizing actives or preservatives.

Vegan Cruelty-Free

Found In Products

The Ordinary

GF 15% Serum for Visible Skin Repair and Wrinkles

INNBEAUTY PROJECT

Extreme Cream Anti-Aging, Firming, & Lifting Refillable Moisturizer

Biossance