Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47. (251/036)

NIC

7/10

Concern level

High concern

Peptide Compound

A recombinant peptide complex produced in Nicotiana benthamiana that combines hexapeptide-40 with a single-chain human recombinant polypeptide-47. It is used in anti-aging formulations to support skin firmness, collagen-related signaling, and visible wrinkle improvement. ([incidecoder.com](https://incidecoder.com/ingredients/nicotiana-benthamiana-hexapeptide-40-sh-polypeptide-47?utm_source=openai))

Pore-clogging

Non-comedogenic

Pregnancy

Safe

Regulatory

No data

Benefits

Boosts Collagen ProductionAnti-agingFirming EffectSupports Barrier Function

Chemical Properties

Molecular Weight

13000 g/mol

pH Range

4.50 - 7.50

Typical Concentration

0.00% - 0.10%

Skin Type Compatibility

dry skin8/10

oily skin6/10

sensitive skin7/10

acne prone6/10

mature skin9/10

normal skin8/10

Interactions

incompatible with: No well-established direct ingredient incompatibilities are publicly documented, Avoid harsh low-pH exfoliant systems if the finished formula is intended for sensitive skin

Risks & Warnings

Low known topical risk overall, but as a novel biotech peptide it has limited publicly available human safety data. Potential concerns are mainly formulation-related: preservative sensitivity, trace protein allergy risk, or irritation in very reactive skin. ([incidecoder.com](https://incidecoder.com/ingredients/nicotiana-benthamiana-hexapeptide-40-sh-polypeptide-47?utm_source=openai))

Vegan Cruelty-Free

Found In Products

Caudalie