Healthy Skinfluence

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2

NIC
8/10
Concern level
High concern
Peptide Compound

A bioengineered fusion peptide derived from Nicotiana benthamiana expression systems, combining Hexapeptide-40 with an sh-polypeptide component. In cosmetics it is used mainly as a skin-conditioning and hair-conditioning active, and is typically positioned in anti-aging or repair-focused formulas. ([cosmileeurope.eu](https://cosmileeurope.eu/inci/detail/23281/nicotiana-benthamiana-hexapeptide-40-sh-polypeptide-2/))

Pore-clogging
Non-comedogenic
Pregnancy
Safe
Regulatory
No data

Benefits

Anti-agingSoothingSupports Barrier Function

Chemical Properties

pH Range
4.50 - 7.50
Typical Concentration
0.00% - 1.00%

Skin Type Compatibility

dry skin8/10
oily skin7/10
sensitive skin7/10
acne prone7/10
mature skin9/10
normal skin8/10

Interactions

incompatible with:

Risks & Warnings

No major topical safety concerns are documented in the available cosmetic references at typical use levels, but as a peptide/protein ingredient it may still be unsuitable for users with unusual sensitivity to bioengineered proteins. Data on concentration-specific safety, pregnancy, and irritation are limited. ([cosmileeurope.eu](https://cosmileeurope.eu/inci/detail/23281/nicotiana-benthamiana-hexapeptide-40-sh-polypeptide-2/))

Vegan Cruelty-Free

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