Magnolol

MAG

5/10

Concern level

Moderate concern

Magnolol is a polyphenolic biphenyl/neolignan from Magnolia species, used in cosmetics mainly as an antioxidant and skin-brightening/soothing active. It is also studied for anti-inflammatory and antimicrobial properties. PubChem lists magnolol with a molecular weight of 266.3 g/mol and notes skin irritation hazards for the pure substance, so cosmetic use should remain low and well-formulated. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/72300?utm_source=openai))

Pore-clogging

Non-comedogenic

Pregnancy

Caution

Regulatory

No data

Benefits

AntisepticBrightening

Chemical Properties

Molecular Weight

266.3 g/mol

pH Range

4.00 - 7.00

Typical Concentration

0.01% - 0.50%

CAS Number: 528-43-8

Skin Type Compatibility

dry skin6/10

oily skin7/10

sensitive skin4/10

acne prone6/10

mature skin8/10

normal skin7/10

Interactions

incompatible with: Use caution when combining with strong exfoliating acids, benzoyl peroxide, or other potentially irritating actives in the same routine if skin is sensitive.

Risks & Warnings

The pure substance is classified on PubChem as a skin irritant, so it may sting or sensitize compromised skin, especially in concentrated or poorly buffered formulas. Because systemic safety data for topical pregnancy use are insufficient and this ingredient is bioactive, conservative pregnancy guidance is to avoid unless the full formulation has been medically reviewed. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/72300?utm_source=openai))

Vegan Cruelty-Free

Found In Products

EADEM

Milk Marvel Dark Spot Serum with Niacinamide and Vitamin C

Naturium

Naturium Multi-Peptide Moisturizer Jumbo, Hydrating & Smoothing Skin Care, Moisturizes with Ethylated Vitamin C & Panthenol, 3.4 oz