Hydroxyproline Palmitamide
Hydroxyproline Palmitamide
HYD
7/10
Concern level
High concern
A lipid-like skin-conditioning ingredient derived from hydroxyproline and palmitic acid. It functions primarily as an emollient/skin-conditioning agent and is commonly used to support a smoother, softer skin feel and improve barrier-related sensory properties in creams and lotions.
Pore-clogging
Low
Pregnancy
Safe
Regulatory
No data
Benefits
MoisturizingSupports Barrier Function
Chemical Properties
pH Range
4.50 - 7.50Typical Concentration
0.10% - 3.00%Skin Type Compatibility
dry skin9/10
oily skin5/10
sensitive skin7/10
acne prone5/10
mature skin8/10
normal skin7/10
Interactions
incompatible with: No well-documented specific incompatibilities, As with other lipidic ingredients, may be less ideal in very heavy occlusive systems for acne-prone users, Can be layered with humectants, ceramides, peptides, and most actives
Risks & Warnings
Available public data are limited, so safety conclusions are conservative. Potential issues are usually formula-dependent irritation or intolerance in very sensitive users. Because it contains a long-chain fatty component, some acne- or malassezia-prone users may prefer lighter formulas.
Vegan Cruelty-Free



