Heptapeptide-6
Heptapeptide-6
HEP
8/10
Concern level
High concern
Peptide Compound
A synthetic seven-amino-acid peptide used as a skin-conditioning anti-aging active. COSMILE identifies it as a synthetic peptide used to maintain skin condition, and supplier/ingredient references describe it as a low-use, generally well-tolerated cosmetic peptide. ([cosmileeurope.eu](https://cosmileeurope.eu/inci/detail/6348/heptapeptide-6))
Pore-clogging
Non-comedogenic
Regulatory
No data
Benefits
Anti-agingSoothingSupports Barrier Function
Chemical Properties
Molecular Weight
832.9 g/mol pH Range
4.00 - 7.00Typical Concentration
0.00% - 0.05%Skin Type Compatibility
dry skin8/10
oily skin7/10
sensitive skin8/10
acne prone7/10
mature skin9/10
normal skin8/10
Interactions
incompatible with: Strong acids or extreme pH may reduce peptide stability, High-heat processing may degrade peptide activity
Risks & Warnings
Low irritation potential overall, but dedicated reproductive, long-term systemic, and human pregnancy datasets are limited. As with peptide actives, patch testing is prudent for highly reactive skin. ([rootsbybenda.com](https://rootsbybenda.com/ingredients/heptapeptide-6?utm_source=openai))
Vegan Cruelty-Free
