Glabridin

GLA

7/10

Concern level

High concern

Glabridin is a licorice-derived isoflavan used in skincare primarily as a brightening and antioxidant active. It is best known for helping reduce the appearance of hyperpigmentation by inhibiting melanin-related pathways, while also providing anti-inflammatory and free-radical-scavenging support. Because it is lipophilic, it is usually incorporated into oil-phase or solubilized delivery systems rather than water-only formulas.

Pore-clogging

Non-comedogenic

Pregnancy

Safe

Regulatory

No data

Benefits

Anti-agingBrighteningHealingSoothing

Chemical Properties

Molecular Weight

324.4 g/mol

Typical Concentration

0.05% - 2.00%

CAS Number: 59870-68-7

Skin Type Compatibility

dry skin7/10

oily skin8/10

sensitive skin6/10

acne prone8/10

mature skin8/10

normal skin8/10

Interactions

incompatible with: No well-established direct contraindications are documented, Use caution when layering with multiple strong brightening actives if irritation occurs, Avoid incompatible high-oxidation or poorly stabilized formulas that may reduce active integrity

Risks & Warnings

Generally considered low-irritation, but sensitive users may experience mild irritation or redness. Main practical risks are product instability, poor solubility, and variable purity/impurities in botanical extracts. As with any brightening active, overuse may increase the chance of irritation. Pregnancy and breastfeeding safety data are limited, so conservative use is advisable.

Vegan Cruelty-Free

Found In Products

Kate Somerville