Chlorhexidine Gluconate
Chlorhexidine Gluconate
CHL
5/10
Concern level
Moderate concern
A cationic biguanide antiseptic and antimicrobial salt form of chlorhexidine used for skin cleansing, oral care, and other antimicrobial applications. In cosmetics and OTC antiseptic products it is valued for persistent broad-spectrum antibacterial activity. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/Chlorhexidine-Gluconate?utm_source=openai))
Pore-clogging
Non-comedogenic
Pregnancy
Safe
Regulatory
No data
Benefits
Antiseptic
Chemical Properties
Molecular Weight
897.8 g/mol pH Range
5.00 - 7.00Typical Concentration
0.05% - 4.00%CAS Number: 18472-51-0
Skin Type Compatibility
dry skin3/10
oily skin5/10
sensitive skin2/10
acne prone4/10
mature skin3/10
normal skin4/10
Interactions
incompatible with: Avoid combining with anionic surfactants/soaps that can reduce activity., Do not layer with products that strongly increase irritation on compromised skin., Avoid use if you have a known chlorhexidine allergy.
Risks & Warnings
Main concern is allergic contact dermatitis and rare but potentially serious immediate hypersensitivity/anaphylaxis. It can irritate eyes and mucous membranes; prolonged or frequent use may dry or irritate skin. ([drugs.com](https://www.drugs.com/monograph/chlorhexidine-gluconate-topical.html?references=1&utm_source=openai))
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