Bis(Tripeptide-1) Copper Acetate
Bis(Tripeptide-1) Copper Acetate
BIS
7/10
Concern level
High concern
Peptide Compound
A copper-complexed peptide, also known as copper tripeptide-1 or prezatide copper acetate. It is used as a signal peptide/skin-conditioning active in anti-aging and repair-oriented formulations, with interest around barrier support, wound-repair signaling, and skin appearance benefits.
Pore-clogging
Non-comedogenic
Regulatory
No data
Benefits
Boosts Collagen ProductionAnti-agingHealingSupports Barrier Function
Chemical Properties
Molecular Weight
862.4 g/mol pH Range
5.00 - 7.00Typical Concentration
0.00% - 0.10%CAS Number: 130120-57-9
Skin Type Compatibility
dry skin7/10
oily skin6/10
sensitive skin5/10
acne prone5/10
mature skin8/10
normal skin7/10
Interactions
incompatible with: avoid very low-pH acid systems, use caution with strong chelators, use caution combining with highly acidic vitamin C formulas, avoid conditions that can destabilize copper-peptide complexes
Risks & Warnings
Evidence for cosmetic benefits is stronger than for major safety concerns, but high copper loads are theoretically irritating and may be poorly tolerated in very sensitive skin. Data for pregnancy-specific use are insufficient. Product performance can be affected by low pH and strong chelators.
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