Biotinoyl Hexapeptide-2 Amide

BIO

8/10

Concern level

High concern

Peptide Compound

Synthetic peptide derivative combining a biotin moiety with a hexapeptide amide. It is used in cosmetic formulas as a skin-conditioning, anti-aging support ingredient and is generally positioned for mature-skin products. Available cosmetic databases describe it as a peptide ingredient used in care formulations for age-related skin concerns. ([cosmileeurope.eu](https://cosmileeurope.eu/inci/detail/20147/biotinoyl-hexapeptide-2-amide/?utm_source=openai))

Pore-clogging

Non-comedogenic

Pregnancy

Safe

Regulatory

No data

Benefits

Anti-agingFirming EffectSupports Barrier Function

Chemical Properties

pH Range

4.50 - 7.00

Typical Concentration

0.00% - 0.05%

Skin Type Compatibility

dry skin8/10

oily skin6/10

sensitive skin7/10

acne prone6/10

mature skin9/10

normal skin8/10

Interactions

incompatible with:

Risks & Warnings

Likely low-risk overall, but as with most peptides, the main concern is individual sensitivity or formulation-related irritation rather than intrinsic toxicity. Data are limited for this specific ingredient, so avoid if a product causes redness, stinging, or contact dermatitis. ([cosmileeurope.eu](https://cosmileeurope.eu/inci/detail/20147/biotinoyl-hexapeptide-2-amide/?utm_source=openai))

Vegan Cruelty-Free

Found In Products

Peace Out