Adapalene
Adapalene
ADA
6/10
Concern level
Moderate concern
Retinoid Compound
Adapalene is a synthetic third-generation retinoid used topically for acne. It normalizes follicular keratinization, helps prevent microcomedone formation, and has anti-inflammatory effects. In cosmetic-style skincare, it functions as a potent acne treatment and texture-smoothing active rather than a hydrator or barrier ingredient.
Pore-clogging
Non-comedogenic
Pregnancy
Caution
Regulatory
No data
Benefits
Boosts Collagen ProductionAcne-fightingAnti-agingImproves Texture
Concerns
Photosensitivity
Chemical Properties
Molecular Weight
412.53 g/mol pH Range
5.00 - 6.50Typical Concentration
0.10% - 0.30%CAS Number: 106685-40-9
Skin Type Compatibility
dry skin3/10
oily skin8/10
sensitive skin3/10
acne prone10/10
mature skin7/10
normal skin7/10
Interactions
incompatible with: benzoyl peroxide, salicylic acid, sulfur, resorcinol, other retinoids, strong exfoliating acids, harsh cleansers
Risks & Warnings
Common risks include dryness, peeling, redness, burning/stinging, and increased photosensitivity, especially during the first weeks of use. Avoid if you are pregnant or trying to conceive unless specifically directed by a clinician. Do not use on eczematous, sunburned, or broken skin. Eye, lip, and mucous membrane contact should be avoided.
Vegan Cruelty-Free
